Recombinant VCAM1 anticorps

N° du produit ABIN7072646

L’anticorps Lapin Chimeric anti-VCAM1 a été validé pour FACS et BP. Il convient pour détecter VCAM1 dans des échantillons de Humain.

Aperçu rapide pour Recombinant VCAM1 anticorps (ABIN7072646)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Peptide (BP)

Clone: B-K9 (C106-K9)

Détail du produit anti-VCAM1 anticorps

Fonction: Anti-CD106 [B-K9 (C106-K9)], Rabbit IgG, kappa

Specificité: B-K9 antibody recognizes CD106 (VCAM1). CD106 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunizing Balb/c mice against activated human umbilical vein endothelial cells (HUVEC).

Isotype: IgG kappa

Information d'application

Indications d'application: B-K9 antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells, and thus it blocks the ability of white blood cells to attach themselves to the activated epithelium during, for instance, inflammation. Consequently, this antibody might be used in research where leukocytes adhesion-blocking is required (Uotila et al., 2014, Wagner et al. 2011).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: CD106

Sujet: VCAM1, Vascular cell adhesion protein 1, V-CAM 1, INCAM-100

UniProt: P19320

Pathways: Carbohydrate Homeostasis